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This work was conceptualized as a result of the proliferation and complexity of reproductive health problems among the urban youths. There is scanty information explaining the factors related to actual practice of home based sex education by parents. The study adopted a correlational design and targeted parents and their adolescent children. Data was analyzed by means of counts, percentages, t-test, F-test and multiple linear regression. It was found that parental education was strongly related to both knowledge and attitudes. Parents who were more knowledgeable and who had more positive attitudes talked more with their children about family life issues. Both parental knowledge and parental attitudes were found to be significant predictors of intention to practice sex education at home. Parents knowledge and socioeconomic status were found to be significant predictors of parental participation in home based sex education. It is recommended that the Government, NGOs, Religious organizations, family life educators and counsellors to develop educational programs targeting parents to help them gain essential skills they may need to communicate effectively about sex education.