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This book will describe ultra low-power, integrated circuits and systems designed for the emerging field of neural signal recording and processing, and wireless communication. Since neural interfaces are typically implanted, their operation is highly energy-constrained. This book introduces concepts and theory that allow circuit operation approaching the fundamental limits. Design examples and measurements of real systems are provided. The book will describe circuit designs for all of the critical components of a neural recording system, including: Amplifiers which utilize new techniques to improve the trade-off between good noise performance and low power consumption. Analog and mixed-signal circuits which implement signal processing tasks specific to the neural recording application: Detection of neural spikes Extraction of features that describe the spikes Clustering, a machine learning technique for sorting spikes Weak-inversion operation of analog-domain transistors, allowing processing circuits that reduce the requirements for analog-digital conversion and allow low system-level power consumption. Highly-integrated, sub-mW wireless transmitter designed for the Medical Implant Communications Service (MICS) and ISM bands.

Micro-power Integrated Circuits for Neural Interfaces Jeremy Holleman Fan Zhang Brian Otis This book describes ultra low-power, integrated circuits and systems designed for the emerging field of neural signal recording and processing, and wireless communication. Since neural interfaces are typically implanted, their operation is highly energy-constrained. This book introduces concepts and theory that allow circuit operation approaching the fundamental limits. Design examples and measurements of real systems are provided. The book describes circuit designs for all of the critical components of a neural recording system, including: Amplifiers which utilize new techniques to improve the tradeoff between good noise performance and low power consumption Analog and mixedsignal circuits which implement signal processing tasks specific to the neural recording application: Detection of neural spikes Extraction of features that describe the spikes Clustering, a machine learning technique for sorting spikes Weakinversion operation of analogdomain transistors, allowing processing circuits that reduce the requirements for analogdigital conversion and allow low systemlevel power consumption. Highlyintegrated, submW wireless transmitter designed for the Medical Implant Communications Service (MICS) and ISM bands. Covers analog, radio, and signal processing theory and design for ultra lowpower circuits, tied together throughout the book to form an entire system; Provides fundamental requirements of neural recording systems, as well as design techniques for reducing power consumption in lownoise amplifiers; Includes miniaturized systemintegration techniques in the context of ultra lowpower circuits; Uses results from real prototype systems to demonstrate techniques described