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InhaltsangabeMaking Methionine: A Love Affair with Folate.- Structure Elucidations of Dimeric Pteridines.- A Selective Procedure for 6-Subsituted Pterin Derivatives: Synthesis and Substitution of Pterin 6-Triflate.- Solution and Solid Phase Synthesis of Pteridines, Purines and Related Compounds.- Synthesis of Pteridines with C-2 and C-6 Functional Group Diversity.- Stereospecific Synthesis of 2-Desamino-Tetrahydropterins as Probes of Hydroxylase Cofactor Recognition.- New Pyranopterin Chemistry Related to Molybdenum and Tungsten Enzymes.- Application of FDCD Spectroscopy for Determination of Chiralities of Biologically Important Pteridines.- Photo-Oxidation of Sepiapterin Produces Pterin-6-Carboxylic Acid and H2O2In Vitro.- Regulation of Tyrosine Hydroxylase by S-Glutathiolation: Relevance to Conditions Associated with Dopamine Neuronal Damage.- The Conformation of Tetrahydro-Biopterin Free and Bound to Aromatic Amino Acid Hydroxylases and NOS.- Regulatory Properties of the Tetrahydropterin Cofactor in the Reaction Catalyzed by Human Tyrosine Hydroxylase Isoforms 1-4.- Structure and Regulation of Phenylalanine Hydroxylase, and Implications for Related Enzymes.- Interaction of Phosphorylated Tyrosine Hydroxylase with 14-3-3 Proteins: Effects on Phosphorylation Kinetics.- Mechanistic Studies of Tryptophan Hydroxylase.- Role of Phe313/Trp326 in Determining Substrate Specificity in Tryptophan and Phenylalanine Hydroxylases.- Possible Contributions of Labile Asparagine Residues to Differences in Regulatory Properties of Human and Rat Phenylalanine Hydroxylase.- 3-(2-Thienyl)-L-Alanine as a Competitive Substrate Analogue and Activator of Human Phenylalanine Hydroxylase.- The N-Terminus of Human Tyrosine Hydroxylase is Responsible for its Association with Phospholipid Bilayers.- Mechanisms of Tyrosine Hydroxylase Activation by Stress Activated Protein Kinases.- Substrate Specificities of Phenylalanine and Tyrosine Hydroxylase: Role of Aspartate 425 of Tyrosine Hydroxylase.- Mutation of W457 Alters N-Hydroxy-L-Arginine Oxidation by Inducible NO Synthase: A Single Turnover Study.- Regulation of Rat Hepatic Phenylalanine Hydroxylating System In Vivo.- Estradiol Modulates GTP Cyclohydrolase I Gene Expression in Brain Catecholaminergic Systems.- PKC-Mediated Regulation of GTP Cyclohydrolase I in Mast Cells and Renal Mesangial Cells.- Regulation of GTP Cyclohydrolase I by Estrogen.- Sexually Dimorphic GTP Cyclohydrolase I Gene Expression is Independent of Sex Hormones.- Studies on the Reaction Mechanism of GTP Cyclohydrolase I.- Site-Directed Mutagenesis of Residues in the Active Site of Sepiapterin Reductase.- Determination of Residues Of Sepiapterin Reductase Phosphorylated by Ca2+/Calmodulin-Dependent Protein Kinase II.- The Interaction of GTP Cyclohydrolase I and GTP Cyclohydrolase Feedback Regulatory Protein Can be Detected Using the Yeast Two-Hybrid System.- Co-Induction of Tetrahydrobiopterin and Catecholamine Syntheses in V-1-Overexpressing PC12D Cells.- Sepiapterin Administration Raises Tissue BH4 Levels More Efficiently than BH4 Supplement in Normal Mice.- Cells Take up BH4, Oxidize it, and the Oxidized Biopterin is Preferentially Released.- Catecholamines-Up, a Negative Regulator of Tyrosine Hydroxylase and GTP Cyclohydrolase I in Drosophila Melanogaster.- The Pteridine Pathway in the Zebrafish, Danio Rerio: Development in Neural Crest-Derived Cells and its Control by GTP Cyclohydrolase I.- Pteridine and Nitric Oxide Biosynthesis in Physarum Polycephalum.- Pteridines and Pigment Granules of Wing Scales Concerned with Sexual Difference in Wing's Capability Reflecting Near-UV Rays in the Japanese Cabbage Butterfly, Pieris Rapae Crucibora.- Tetrahydrobiopterin, Nitric Oxide Synthesis and cGMP Concentrations in Mutants of Physarum Polycephalum with Altered Sporulation Behavior.- BH4 and NOS are Involved in Light Controlled Development of Sporangiophores in the Fungus Phycomyces Blakesleeanus.- Determination of Tetrahydropterins as Native Pteridi